Dorothy E. Blake, 100, of Lesage, WV, passed away Monday, May 10, 2021, in the Emogene Dolin Jones Hospice House, Huntington. She was born October 10, 1920 in Lesage, WV a daughter of the late George Cleveland and Cora Ethel Berry Brewer. She was also preceded in death by her husband, Anse Blake, Sr.; three sons, Anse "Sonny" Blake, Jr., Wayne V. Blake and Darrell K. Blake; five sisters, Ola Chapman, Irene Templeton, Olive Little, Addie Roy, and Ethel Sharp; and three brothers, Kenneth Brewer, Patrick "Pat" Brewer, and Woodrow "Woody" Brewer. She had her own housecleaning and caregiving business. She attended Olive Missionary Baptist Church and Oak Hill UBI Church with her children. Survivors include: a daughter, Imogene "Jean" (James) Fritz of Lesage, WV; a son, Lowell "Tommy" Blake of Glenwood, WV; twelve grandchildren; 28 great grandchildren; six step great grandchildren and eleven great great grandchildren. Funeral services will be conducted 2:00 pm Saturday, May 15, 2021, at Chapman's Mortuary, Huntington, with Pastor Gordon Rutherford and Pastor Jamie Jefferson officiating. Burial will be in Greenbottom Memorial Park, Lesage, WV. Visitation will be from 6:00 to 8:00 pm Friday, May 14, 2021, at the funeral home.