Karlene Pamella Brown Henderson, 67, "Miss B", of Barboursville, WV, formerly of Huntington, WV, passed away Thursday, February 18, 2016, at home surrounded by her family. Funeral services will be conducted 10:00 am Wednesday, February 24, 2016, at Chapman's Mortuary, Huntington, with her son, Pastor Toney Henderson, officiating. Burial will be in White Chapel Memorial Gardens, Barboursville. She was born June 14, 1948 in Springfield, OH a daughter of the late Carl and Eileen Hill Brown of Springfield, OH. She was also preceded in death by her loving husband, Johnny Lee Henderson; a sister, Mary (Peachie) Folk of Springfield, OH and a brother, Darold Brown of Huber Heights, OH. Survivors include: her children, Samantha (Junior) Crockett of Barboursville, WV, Mary Christine Holley (Dwayne Maynard) of Ashland, KY, Toney (Lou) Henderson of Dallas, NC and Kathlene Laray Taylor (Josh "Fuzz" Worrell) of Huntington; three brothers and one sister of Ohio; one special granddaughter whom she raised as her own Pamela (Josh) Beckleheimer of Huntington; one special grandson whom she raised as her own, Jonathon Corey Henderson; ten more grandchildren whom she cherished, Zachary Henderson, Samira Henderson, Jessica Bragg, Anthony Taylor, Hayden Taylor, Stephen Curry, Christopher Holley, Lydia Holley, and Savanna and Cameron Worrell; and 15 great grandchildren. She was loved by many friends and family. In lieu of flowers, the family requests that donations be made to the funeral home to help offset expenses. Visitation will be from 6:00 to 8:00 pm Tuesday, February 23, 2016, at Chapman's Mortuary.